Úroveň pokročilosti: Introductory Topic

Junior Biophysicist

Cytoskeleton Remodeling as a Potential Regulator of Metabolic Rewiring in Liver Cancer Cells Emerging evidence has revealed that physical stimuli from the cellular microenvironment play a crucial role in transmitting mechanical signals that regulate key cellular functions such as proliferation, migration, and malignant transformation [1-3]. It is now clear that tumor cells are subjected to…

4G/5G remote communication and data acquisition – 2

Proton exchange membranes are the important part of proton exchange membrane fuel cells (PEMFCs) which is considered as one promising clean and highly efficient power generation technology in 21st century. The currently available proton exchange membranes are not stable under long-term usage and are not economical. Despite the currently promising achievements of PEMFCs, there are…

4G/5G remote communication and data acquisition – 1

To implement a robust and efficient stack for a selected embedded platform (such as STM32, ARM Linux, or ESP32) with reliable and secure (properly encrypted) data transfer on 4G (LTE) network and to add support for some leading industry-standard protocols – IEC 104, DLMS, BACnet,… https://www.fm.tul.cz

Benchmark of selected algorithms on acceleration cards

The aim of this work is to create benchmark computational tasks for AMD VCK5000 and AMD Alveo U50LV accelerator cards, investigating data throughput and computational performance on typical tasks such as matrix multiplication, FT computation or neural network inference. The benchmark will be compared to the same (or at least similar) tasks solved on GPUs…

Platform for synchronized remote audio signal collection

The acquisition of audio signals using MEMS microphones is limited by the length of the data wires. The microphones can be operated on a printed circuit board or at a very short distance from the receiver. Using differential wiring, the range could be extended using standard cabling and connectors (UTP). The objective of this work…

Effective Strategies for the Production of Recombinant 2A Protease Enteroviruses (A71 and D68) for Subsequent Design of Protease Inhibitors

Enteroviruses (EVs) are single-stranded RNA viruses with positive polarity that cause widespread diseases with significant health and economic impacts, commonly affecting both young children and adults. They are the most frequent causative agents of viral respiratory and neurological infections. While they typically cause mild symptoms, they can also lead to severe issues such as acute…

Diagnostics of Reactive Plasma Using a Planar High-Frequency Probe During the Deposition of Layers with Antiviral Effects

As part of the internship, the student will be involved in the research of plasma deposition of crystalline CuFeO2 layers with antiviral effects. The deposition of CuFeO2 layers will be carried out using the method of reactive pulsed magnetron sputtering with an additional high-frequency inductively coupled plasma operating in resonance with the electron cyclotron wave.…

A Look into the Heart of Affinity Biosensors: Custom Biochip Development

During this internship, the student will first become familiar with the fundamental principles of modern affinity optical and piezoelectric biosensors, which target the analysis of real, and therefore complex, biological samples, with a focus on public safety, clinical diagnostics, and food safety. The student will learn measurement techniques such as surface plasmon resonance (SPR) and…

Preparation and Optimization of Inorganic Crystals for the Detection of Ionizing Radiation

During the internship, the student will become familiar with the characterization and preparation of crystals for scintillation detectors of ionizing radiation. The crystals will be prepared using the modern micro-pulling-down method, which is currently available only at the Institute of Physics of the Czech Academy of Sciences. The influence of composition (stoichiometry) of gadolinium-gallium-aluminum garnet-based…

Detection of pathogens or antibodies against pathogens using the series of LSPR active nanocomposites

The main aim of this study is to develop a new detection system for selected bacteria and viruses, as well as their proteins and antibodies against them. The detection system is focused on the localized surface plasmon resonance (LSPR) where pathogen/protein/antibody attached to the LSPR sensors (containing metal nanoparticles) changes the optical and electrical characteristics.…