Obor: Biology

Internship in Biosensor Technologies for Field Applications

At the Laboratory of Functional Biointerfaces at the Institute of Physics of the Czech Academy of Sciences, we focus on developing a new generation of affinity biosensors capable of reliably analyzing complex biological samples directly in the field.We combine optical and piezoelectric detection systems with the latest approaches in microfluidics and additive manufacturing to create…

Studying Life at the Level of Individual Molecules

At our Dioscuri Centre team at FZU of the CAS, we develop cutting-edge microscopes that allow us to observe individual biomolecules in real time and in their natural state – without the need for fluorescent labeling. Our focus is on seeing and understanding what happens inside cells and molecular systems that form the basis of…

Junior Biophysicist

Cytoskeleton Remodeling as a Potential Regulator of Metabolic Rewiring in Liver Cancer Cells Emerging evidence has revealed that physical stimuli from the cellular microenvironment play a crucial role in transmitting mechanical signals that regulate key cellular functions such as proliferation, migration, and malignant transformation [1-3]. It is now clear that tumor cells are subjected to…

Detection of pathogens or antibodies against pathogens using the series of LSPR active nanocomposites

The main aim of this study is to develop a new detection system for selected bacteria and viruses, as well as their proteins and antibodies against them. The detection system is focused on the localized surface plasmon resonance (LSPR) where pathogen/protein/antibody attached to the LSPR sensors (containing metal nanoparticles) changes the optical and electrical characteristics.…

Functional nanolayers for the real world

At the Laboratory of Functional Biointerfaces at the Institute of Physics of the Czech Academy of Sciences, we focus on the development and study of functional nanolayers that can resist unwanted surface contamination – so-called antifouling coatings. These special surfaces find broad applications in medicine, biosensing, and industry. Our goal is to understand and control…

Segmentation of 2D biological objects

Segmentation of 2D biological objectsThe focus of the proposed work is the development of computer vision methods with an emphasis on object segmentation in 2D data. In collaboration with microbiologists, data will be analysed with specific tasks. The study will include the selection of appropriate metrics to compare the performance of different segmentation methods. Based…