Effective strategies to produce recombinant 2Apro of enteroviruses (A71 and D68) for the subsequent design of protease inhibitors
Enteroviruses (EVs) are single-stranded RNA viruses with positive polarity whose members cause widespread human diseases with major health and economic impacts, commonly observed in young children and adults. They are the most common etiologic agents of viral respiratory and neurological infections, usually causing mild symptoms but capable of causing severe pathology, including acute asthma exacerbations,…